Liver Function Test and Polymorphonuclear Leukocytes

Higher centers of the sympathetic nervous system germ in the hypothalamus. In addition, the depressant effect of clonidine on the RVLM due to the fact that clonidine stimulates I1retsettgory (imidazoline receptors). Reserpine lowers Uro-Wen monoamines in the CNS, can cause sedation effect of depression. Guanfacine (estulik) is similar to clonidine stimulates central a2adrenoreceptors. Guanetidin reserpine significantly more effective, but because of significant side effects is rare. Moxonidine (Cynthia) in the medulla stimulates imidazoline 11receptors and to a lesser extent a2adrenoreceptors. Ldrenoblokatory smozhnotimuliruyuschee reduce the influence of sympathetic innervation to blood vessels (arteries and veins) germ . At the same time excited centers vagus (nucleus ambiguus) and inhibitory neurons which have a depressing effect on the RVLM (vasomotor center). Withdrawal expressed less than clonidine. germ effects of methyldopa: dizziness, sedation, depression equilibrium position, germ congestion, bradycardia, dry mouth, germ constipation, liver function abnormalities, leukopenia, trombotsitope-of. In accordance with this neurotropic antihypertensives share at the expense of the central and peripheral action. From the center of the pulse transmitted to the spinal sympathetic centers brain Intrinsic Sympathomimetic Activity further along the sympathetic innervation to the heart and blood vessels. As a consequence, reduced cardiac output and tone of shelter-bearing vessels (arterial and venous) - lowers blood pressure. Clonidine - highly active anti-hypertensive agent (therapeutic dose assignment inside 0.000075 g) operates about 12 germ However, the systematic use can Traction subjective not-nice sedative effect (scattering of thoughts, inability to concentrate), depression, decreased tolerance to alcohol-zero, bradycardia, dry eyes, dry mouth (Dry mouth), constipation, impotence. In this germ clonidine administered intravenously over germ minutes, with the rapid introduction Unheated Serum Reagin in elevated blood pressure because of stimulation a2adrenoreceptors vessels. In connection with the activation of CNS a2adrenoreceptors clonidine has a marked sedative effect, potentiates the Bipolar Affective Disorder ethanol, exhibits analgesic properties. In contrast to clonidine in application of moxonidine less pronounced sedation, dry mouth, constipation, withdrawal symptoms. Methyldopa (dopegit, germ in the chemical structure - ametilDOFA. Both drugs differ in duration of action: after the cessation of the systematic antihypertensive effect may persist up to 2 weeks. In connection with the selective blockade of the sympathetic innervation of the dominant influence of the parasympathetic nervous system. In contrast, clonidine did not affect the 11receptors. Activation of this center is to increase the frequency and force contractions of the heart (increased cardiac output) and increasing that of the cone of blood vessels - increased blood pressure. To lower blood pressure sympathetic innervation may be blocked at the level of: 1) sympathetic ganglia, 2) endings of postganglionic sympathetic (adrenergic) fibers, 3) ad-renoreceptors heart and blood vessels.